منابع مشابه
Aldosterone as a cardiovascular risk hormone.
The pathophysiological role of aldosterone in the development of cardiovascular disease has long been considered to be due its potent volume expansion/hypertensive effect mainly via mineralocorticoid receptor (MR) expressed in renal tubular epithelial cells. However, recent accumulating lines of evidence from clinical and experimental studies have suggested that direct cardiovascular effect of ...
متن کاملCardiovascular Risk Reduction with Renin-Angiotensin Aldosterone System Blockade
This paper examines the evidence supporting treatments within the renin-angiotensin aldosterone system (RAS), the role cardioprotection plays within the management of hypertension, considerations around medication adherence, and the role of the nurse or nurse practitioner in guiding patients to achieve higher hypertension control rates. A large body of data now exists to support the use of angi...
متن کاملAldosterone and cardiovascular disease.
Aldosterone is an adrenal hormone that regulates sodium, fluid, and potassium balance. Jerome Conn first described the syndrome of autonomous and excessive aldosterone secretion or "primary aldosteronism." Contrary to the historical belief, recent studies indicate that primary aldosteronism is a common cause of hypertension with a prevalence of 5-10% among general hypertensive patients. Various...
متن کامل[Renal disease as a cardiovascular risk factor].
Mailing Address: Roberto Jorge da Silva Franco • Rua Carlos Guadanini, 1805 18610-120 – Botucatu, SP Brazil E-mail: [email protected] An estimated 10% of the American population has some degree of renal disease, although asymptomatic. In Brazil, no data are available on the prevalence of chronic renal disease. A number of studies show a direct and close relationship between the degree of re...
متن کاملCardiovascular risk factor investigation: a pediatric issue
OBJECTIVES To correlate cardiovascular risk factors (e.g., hypertension, obesity, hypercholesterolemia, hypertriglyceridemia, hyperglycemia, sedentariness) in childhood and adolescence with the occurrence of cardiovascular disease. SOURCES A systematic review of books and selected articles from PubMed, SciELO and Cochrane from 1992 to 2012. SUMMARY OF FINDINGS Risk factors for atheroscleros...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2010
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2010.08.005